The kinematics of cytotoxic lymphocytes influence their ability to kill target cells.
Cytotoxic lymphocytes (CTL) have been reported to show a range of motility patterns from rapid long-range tracking to complete arrest, but how and whether these kinematics affect their ability to kill target cells is not known.Many in vitro killing assays utilize cell lines and tumour-derived cells as targets, which may be of limited relevance to t